The use of tirzepatide in patients with Hashimoto's disease requires comprehensive safety evaluation and ongoing medical supervision
While waiting for the outcome of the SURPASS-CVOT, we look at one study known as the SURMOUNT-1 trial that included obese patients with weight-related complications such as hypertension, dyslipidemia, sleep apnea or cardiovascular diseases
In addition to their insulinotropic effects, GIP and GLP-1 play critical roles in various biological processes in different tissues and organs that express GIPR and GLP-1R, including the pancreas, fat, bone and the brain
This distal location presents problems explaining the rapid release after a meal
Tailoring the approach improves comfort, safety, and long-term stability
Lesson learned